The CRISPR bacteria connection

Heard the word "CRISPR" mentioned in genetics-related stories recently? Do you know how it was developed? This new article from Genetics Home Reference explains the bacteria connection!

"CRISPR-Cas9 was adapted from a naturally occurring genome editing system in bacteria. The bacteria capture snippets of DNA from invading viruses and use them to create DNA segments known as CRISPR arrays. The CRISPR arrays allow the bacteria to "remember" the viruses (or closely related ones). If the viruses attack again, the bacteria produce RNA segments from the CRISPR arrays to target the viruses' DNA. The bacteria then use Cas9 or a similar enzyme to cut the DNA apart, which disables the virus."

Genetics Home Reference from the National Library of Medicine is useful resource to learn about how genes and health are connected.


Websites Referenced
https://ghr.nlm.nih.gov/primer/genomicresearch/genomeediting
https://ghr.nlm.nih.gov/
https://www.nlm.nih.gov/ 

Now Online - Bowden and Greenberg Pediatric Nursing Procedures, 4th ed.,

Bowden and Greenberg's Pediatric Nursing Procedures (4th ed., 2016) is now available online throughout the hospital and remotely! This is the nursing standard used by the hospital.

There are links to it in several places on the library website: 

•  on the Online Catalog page  
•  via the Nursing Information article on the Links page

It is also accessible remotely via OpenAthens (contact the library for an account). Find the title in the center panel under "Looking for an online book."

If you need assistance, just contact the Medical Library. Be sure to log off when done so that others can also use it.

Websites Referenced

https://online.statref.com/Document.aspx?grpalias=TSRH&fxid=718

http://tsrhkids/mlibrary/

http://tsrhkids/mlibrary/online_catalog.htm

http://tsrhkids/mlibrary/links.htm

http://auth.athensams.net/my/

DeBakey Papers Now NLM Digital Archive

Dr. Michael DeBakey, known for the coronary bypass, is now featured in the archives of the National Library of Medicine. Selections from the Michael E. DeBakey Papers collection, including publications, speeches, drawings, correspondence, portraits, oral history interviews and video recordings, can be freely viewed online. His advocacy is a big reason the National Library of Medicine exists today. NLM has also launched a fellowship program in his honor.

DeBakey “translated his expertise in the OR into political and policy capital on local, national and international levels to affect medical research funding, medical education and broader disease awareness” said Dr. Shelley McKellar, Hannah Chair in the History of Medicine at Western University in London, Canada, speaking at the first annual NLM Michael DeBakey Lecture in the History of Medicine on March 2, 2017.

From a story by Dana Talesnik, NLM in Focus, May 9, 2017.

Websites referenced

https://profiles.nlm.nih.gov/FJ/

https://www.nlm.nih.gov/hmd/informationfor/debakeyfellowship.html

http://history.uwo.ca/People/Faculty/mckellar.html

https://infocus.nlm.nih.gov/2017/05/09/the-texas-tornado-nlm-commemorates-heart-surgeon-debakey/

https://nihrecord.nih.gov/newsletters/2017/05_05_2017/story2.htm

NLM Associate Fellow Visits TSRHC Libraries

The TSRHC hospital libraries were visited by representatives of the National Library of Medicine today. Tyler Moses, an NLM Associate Fellow, came to north Texas to spend time at the National Network of Libraries South Central Region (NNLM SCR) headquarters. Dan Burgard is Director of the NNLM SCR program, which is based at the Lewis Library at UNT Health Science Center in Fort Worth and supports 5 states.

While at the hospital Moses and Burgard met with Mary Peters (Medical Library) and with Mary Anne Fernandez and Jill Johnson (Family Resource Center) to tour the Brandon Carrell Medical Library and the Christi Carter Urschel Family Resource Center. Moses has just completed her Fort Worth visit and will now visit the UT Southwestern Library in Dallas for several day

The NLM Associate Fellowship Program is a highly selective one year postgraduate training opportunity at the NLM in Bethesda, Maryland. Moses is one of only 4 fellows in the class of 2016-17. The program provides a broad foundation in heath sciences information services as preparation for future leadership roles in health sciences libraries and in health services research.  

photo by Rick Smith, TSRHC Communications

Websites Referenced

https://www.nlm.nih.gov/

https://www.nlm.nih.gov/about/training/associate/meettheassociates.html

https://www.nlm.nih.gov/about/training/associate/

https://nnlm.gov/scr

Eugene Garfield, a Pioneer in Information Science

Eugene Garfield can certainly be considered one of the giants of information science. Garfield’s life, as shared in his obituary by Subbiah Arunachala, is intertwined with the history of the development of machine indexing and use of the computer’s capability to enable access to scientific papers by exploring the basic tool of the citation.  This pioneer in information studies created Current Contents, Science Citation Index and his company ISI. He did groundwork that led to the Medical Subject Headings (MeSH). He made great leaps by recognizing the value of the citation itself and developing a way to make them more accessible to researchers. 

Websites Referenced

https://en.wikipedia.org/wiki/Standing_on_the_shoulders_of_giants

http://www.currentscience.ac.in/Volumes/112/06/1282.pdf

https://meshb.nlm.nih.gov/#/fieldSearch

His website:  http://www.garfield.library.upenn.edu/

His essays:  http://garfield.library.upenn.edu/category.html

including Was the Science Citation Index concept inevitable? (mentions the value of the citation). Link at http://www.garfield.library.upenn.edu/geneticscitationindex.html

 

Additional tributes:
http://www.against-the-grain.com/2017/03/atg-newschannel-original-the-passing-of-a-giant-eugene-garfield-dies-at-90/ 

Unpaywall, a new tool to locate free full text

Here’s a new way to find full text content offered freely somewhere online! 

Easily install Unpaywall’s little lock symbol to your tool bar (Chrome or Firefox required). Then if you encounter an article for which a free full text source is available, a larger lock will appear on the right. A simple click takes you to the article. Since Unpaywall only matches with legally uploaded versions, it can be a great addition to your web search tools and will compliment other resources you may use.

   

Unpaywall should be officially released in early April, and developer Impactstory welcomes input.

Websites Referenced

http://unpaywall.org/

http://unpaywall.org/faq

http://blog.impactstory.org/unpaywall/

Journals - What’s New in Your Favorites? Easy eTOCs!

A new PubMed Labs experiment offers a super awareness tool, PubMed Journals. It is a fast and current way to follow the latest releases from your favorite health science journals that are indexed in MEDLINE – or at least know when they show up in PubMed. First you do need to have a My NCBI account, a service that offers lots more useful features and doesn’t send you junk mail. Once you have that, set it to stay signed in so any time you go to PubMed you’ll be in your account. If you want to see what the library offers, be sure to use our unique address (or this one if you are on staff at the med school).

Then locate PubMed Journals in the lower left of the PubMed home page. Enter a title in the search box at PubMed Journals (if you type slowly a suggestion list will appear!). No additional sign-in is needed, no registration at the publisher website. No email alerts clogging up your in-box! Your list of titles followed is right on the page. Easily discontinue by clicking “Following” to “Follow” – the title will disappear from the list the next time you return to the page. The page also lists popular journals for easy access.

A tip – to return to PubMed from PubMed Journals or My NCBI, just scroll to the very bottom to click on PubMed in the “Popular” column.

Add PubMed Journals to your own “Popular” list of websites today!

Websites Referenced

https://ncbiinsights.ncbi.nlm.nih.gov/2016/09/07/pubmed-journals/ (and check the comments section there to learn more and provide development input!)

https://www.ncbi.nlm.nih.gov/myncbi/

http://boneuponlibrarynews.blogspot.com/2015/12/my-ncbi-valuable-tool-for-proactive.html

http://www.ncbi.nlm.nih.gov/pubmed/?holding=txudtslib
http://www.ncbi.nlm.nih.gov/pubmed/?holding=txudtslib,utswmlib 

https://www.ncbi.nlm.nih.gov/labs/journals/